Adherens Junctions: from Molecular Mechanisms to Tissue by Tony Harris

By Tony Harris

Cell–cell adhesion is prime for the advance and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the simplest understood cell-cell adhesion complexes. during this quantity, a bunch of across the world well-known specialists stories AJ biology over a variety of association; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and total animal improvement. AJs have additionally been an essential component of animal evolution, and play primary roles in melanoma improvement, pathogen an infection and different illnesses. This publication addresses significant questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins have interaction to collect AJs and mediate adhesion?
• How do AJs interface with different mobile equipment to couple adhesion with the full telephone?
• How do AJs have an effect on cellphone behaviour and multicellular improvement?
• How can irregular AJ job bring about disease?

Show description

Read or Download Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease: 60 (Subcellular Biochemistry) PDF

Best developmental biology books

The Zebrafish: Cellular and Developmental Biology: Vol 76 (Methods in Cell Biology)

This quantity of equipment in cellphone Biology, the 1st of 2 components near to zebrafish, presents a complete compendia of laboratory protocols and studies masking the entire new equipment constructed given that 1999. this primary quantity offers state of the art descriptions of novel mobile imaging applied sciences and strategies for tradition of zebrafish stem cells, summarizes protocols for analyzingthe improvement of significant organ platforms together with the vital anxious process (CNS), and introduces using the zebrafish as a version approach for human ailments.

Principles of Regenerative Medicine

Almost any ailment that effects from malfunctioning, broken, or failing tissues can be most likely cured via regenerative drugs treatments, by way of both regenerating the broken tissues in vivo, or via transforming into the tissues and organs in vitro and implanting them into the sufferer. rules of Regenerative medication discusses the newest advances in know-how and medication for exchanging tissues and organs broken through affliction and of constructing remedies for formerly untreatable stipulations, corresponding to diabetes, center disorder, liver illness, and renal failure.

Mouse Development: Patterning, Morphogenesis, and Organogenesis

This ebook represents a vintage compilation of present wisdom approximately mouse improvement and its correlates to investigate in phone biology, molecular biology, genetics, and neuroscience. Emphasis is put on the learn process, experimental layout, and important research of the information, disguishing this from different books that merely specialise in protocols for mouse developmental examine.

Genetic Transformation Systems in Fungi, Volume 1 (Fungal Biology)

A number of varied transformation thoughts were constructed through the years and easily proven to be decisive equipment in fungal biotechnology. This publication will hide the fundamentals at the back of the main customary transformation tools, in addition to linked instruments and methods. each one bankruptcy will offer protocols besides examples utilized in laboratories all over the world.

Additional info for Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease: 60 (Subcellular Biochemistry)

Example text

Download PDF sample

Rated 4.61 of 5 – based on 25 votes