Biological Reactive Intermediates Vi: Chemical and by Patrick M. Dansette,Robert R. Snyder,Terrence J. Monks,David

By Patrick M. Dansette,Robert R. Snyder,Terrence J. Monks,David J. Jollow,I. Glenn Sipes,Helmut Greim,G. Gordon Gibson,Marcel Delaforge

This quantity provides a dialogue of the organic results produced following the metabolism of xenobiotic chemical substances to chemically reactive metabolites, that's, poisonous and carcinogenic results, that have been the foundation of all 5 past volumes during this sequence. specifically, this quantity devotes sections to structure-activity relationships, advances within the figuring out of the chemistry of reactive metabolites, and the iteration and job of reactive oxygen species with precise emphasis on nitric oxide. There also are segments on DNA harm through reactive metabolites and DNA fix, tissue particular responses to BRIs, and human future health results of BRIs. The papers that include this quantity have been submitted by way of scientists who have been in attendance on the Symposium on organic Reactive Intermediates VI on the Universite Rene Descartes, July 16-20, 2000.

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