By Brian K. Hall
Bones and Cartilage presents the main in-depth assessment and synthesis assembled at the subject, throughout all vertebrates. It examines the functionality, improvement and evolution of bone and cartilage as tissues, organs and skeletal structures. It describes how bone and cartilage enhance in embryos and are maintained in adults, how bone is repaired once we holiday a leg, or regenerates whilst a newt grows a brand new limb, or a lizard a brand new tail.
The moment variation of Bones and Cartilage comprises the newest wisdom of molecular, mobile, developmental and evolutionary tactics, that are built-in to stipulate a unified self-discipline of developmental and evolutionary skeletal biology. also, assurance contains how the molecular and mobile facets of bones and cartilage fluctuate in numerous skeletal structures and throughout species, besides the most recent stories and hypotheses of relationships among skeletal cells and the latest details on coupling among osteocytes and osteoclasts All chapters were revised and up-to-date to incorporate the newest examine.
- Offers whole insurance of each point of bone and cartilage, with up to date references and vast illustrations
- Integrates improvement and evolution of the skeleton, to boot a synthesis of differentiation, progress and patterning
- Treats all degrees from molecular to scientific, embryos to evolution, and covers all vertebrates in addition to invertebrate cartilages
- Includes new chapters on evolutionary skeletal biology that spotlight general edition and variability, and edition outdoor the norm (neomorphs, atavisms)
- Updates hypotheses at the origination of cartilage utilizing new phylogenetic, mobile and genetic data
- Covers stem cells in embryos and adults, together with mesenchymal stem cells and their use in genetic engineering of cartilage, and the idea that of the stem mobile niche
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